ⓘ Fatty acid amide hydrolase

                                     

ⓘ Fatty acid amide hydrolase

Fatty acid amide hydrolase or FAAH is a member of the serine hydrolase family of enzymes. It was first shown to break down anandamide in 1993. In humans, it is encoded by the gene FAAH.

                                     
  • signalling is controlled in part by fatty acid amide hydrolases which convert the amide to the parent fatty acid One example of signaling is induced
  • Fatty acid amide hydrolase 2 or FAAH2 EC 3.5.1.99, oleamide hydrolase 2, anandamide amidohydrolase 2 is a member of the serine hydrolase family of enzymes
  • N - acylethanolamine acid amide hydrolase NAAA EC 3.5.1 - is a member of the choloylglycine hydrolase family, a subset of the N - terminal nucleophile hydrolase superfamily
  • 4 - Nonylphenylboronic acid is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase FAAH with an IC50 of 9.1nM, and 870x selectivity
  • glycan hydrolases including protein phosphate methylesterase 1, acyloxyacyl hydrolase and sialic acid acetylesterase Some amidases, including fatty acid amide
  • is a potent and exquisitely selective inhibitor of the enzyme fatty acid amide hydrolase FAAH with an IC50 of 7.2nM, and both analgesic and antiinflammatory
  • molecule. It was first described in 1998 as being an inhibitor of fatty acid amide hydrolase FAAH In 2007, it was shown to have analgesic properties and
  • KDS - 4103 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase FAAH FAAH is the primary degradatory enzyme for the endocannabinoid
  • Retrospective: Elevating Anandamide AEA by Targeting Fatty Acid Amide Hydrolase FAAH and the Fatty Acid Binding Proteins FABPs Frontiers in Pharmacology
  • PF - 3845 is a selective inhibitor of fatty acid amide hydrolase It results in increased levels of anandamide and results in cannabinoid receptor - based
  • the amide derived from the fatty acid oleic acid It is a colorless waxy solid and occurs in nature. Sometimes labeled as a fatty acid primary amide FAPA
  • inhibitors attenuate the breakdown of anandamide by the enzyme fatty acid amide hydrolase FAAH in cell culture. One of these inhibitors SB - FI - 26 isolated