ⓘ Ovarian germ cell tumors

                                     

ⓘ Ovarian germ cell tumors

Ovarian germ cell tumors are heterogeneous tumors that are derived from the primitive germ cells of the embryonic gonad, which accounts for about 2.6% of all ovarian malignancies. There are four main types of OGCTs, namely dysgerminomas, yolk sac tumor, teratoma, and choriocarcinoma.

Dygerminomas are the most common type and is especially noticeable in patients with a diagnosis of gonadal dysgenesis. OGCTs are relatively difficult to detect and diagnose in early stages because of the nonspecific histological features. Common symptoms OGCT flatulence, bloating, ascites and dyspareunia. OGCT arises mainly due to the formation of malignant cells in the primary germ cells of the ovary. However, the exact pathogenesis of OGCTs still unknown, revealed various genetic mutations and environmental factors. OGCTs are often found during pregnancy, when the adventitious mass is detected during a pelvic examination, ultrasound shows a solid mass in the ovary or the study of blood serum shows elevated alpha-fetoprotein levels. They are unlikely to have metastases, and hence the level of the control tumors is surgical resection in combination with chemotherapy. Frequency of occurrence is less than 3% worldwide.

                                     
  • A germ - cell tumor GCT is a neoplasm derived from germ cells Germ - cell tumors can be cancerous or benign. Germ cells normally occur inside the gonads
  • 30 of ovarian tumors but only 5 of ovarian cancers, because most germ cell tumors are teratomas and most teratomas are benign. Germ cell tumors tend to
  • of ovarian diseases. Some of the ovarian diseases or disorders are: Endometriosis. Ovarian cysts. Ovarian Epithelial Cancer. Ovarian Germ Cell Tumors Ovarian
  • An Extracranial Germ - Cell Tumor EGCT occurs in the abnormal growth of germ cells in the gonads testes or ovaries and the areas other than the brain
  • Germ cell tumors of the ovary develop from the ovarian germ cells Germ cell tumor accounts for about 30 of ovarian tumors but only 5 of ovarian cancers
  • epithelial ovarian tumors Cord - stromal and germ cell belong to the nonepithelial category which are much less common. According to research, most ovarian cancers
  • is a tumor of germ cell origin, containing tissues from more than one germ cell line. It can be ovarian or testicular in its origin. An ovarian teratoma
  • all ages. As of 2018, germ cell tumors account for 3 of all cancers in children and adolescents 0 - 19 years old. Germ cell tumors are generally located
  • doi: 10.1097 GCO.0b013e3283527dcf. ISSN 1040 - 872X. PMID 22487725. Ovarian Germ Cell Tumors Treatment National Cancer Institute. 1980 - 01 - 01. Retrieved 2017 - 12 - 01