ⓘ Prickle planar cell polarity protein 2

                                     

ⓘ Prickle planar cell polarity protein 2

This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5.

                                     
  • movement of nerve cells The first prickle protein was identified in Drosophila as a planar cell polarity protein Vertebrate prickle - 1 was first found
  • Prickle planar cell polarity protein 1 is a protein that in humans is encoded by the PRICKLE 1 gene. This gene encodes a nuclear receptor that may be a
  • it is a membrane protein Prickle is another protein in the planar cell polarity signaling pathway. Prickle is recruited to the cell surface membrane
  • Prickle - like protein 4 is a protein that in humans is encoded by the PRICKLE 4 gene. GRCh38: Ensembl release 89: ENSG00000278224 - Ensembl, May 2017 GRCm38: