ⓘ Coiled-coil domain containing 115

                                     

ⓘ Coiled-coil domain containing 115

The protein encoded by this gene has been observed to localize to the endoplasmic reticulum ER-Golgi intermediate compartment ERGIC and coat protein complex I COPI vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferation and suppresses cell death. Defects in this gene are a cause of congenital disorder of glycosylation, type IIo in humans.