ⓘ Cathepsin O

                                     

ⓘ Cathepsin O

Cathepsin O is a cysteine protease and a member of the cathepsin family and papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cysteine proteinase.

                                     
  • Cathepsin L2 or V cysteine protease Cathepsin O cysteine protease Cathepsin S cysteine protease Cathepsin W cysteine proteinase Cathepsin Z
  • Cathepsin K, abbreviated CTSK, is an enzyme that in humans is encoded by the CTSK gene. The protein encoded by this gene is a lysosomal cysteine protease
  • cathepsin B, cathepsin C, cathepsin G, cathepsin H, cathepsin K, cathepsin L, cathepsin L2 or V, cathepsin O cathepsin S, cathepsin Z, and cathepsin
  • non - pepsin proteinase, cathepsin D - like acid proteinase, cathepsin E - like acid proteinase, cathepsin D - type proteinase is an enzyme. Cathepsin E is a protease
  • Cathepsin G is a protein that in humans is encoded by the CTSG gene. It is one of the three serine proteases of the chymotrypsin family that are stored
  • Cathepsin B is in humans encoded by the CTSB gene. Cathepsin B belongs to a family of lysosomal cysteine proteases and plays an important role in intracellular
  • Cathepsin S is a protein that in humans is encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this
  • Cathepsin L2, also known as cathepsin V and encoded by the CTSV gene, is a human gene. The protein encoded by this gene, a member of the peptidase C1
  • compartment by lysosomes. Of these hydrolytic enzymes, cathepsin K is of most importance. Cathepsin K is a collagenolytic, papain - like, cysteine protease
  • Nitroxoline has been shown to inhibit the enzymatic activity of cathepsin B. Cathepsin B degrades extra - cellular membrane proteins in tumor cells, allowing
  • is associated with cathepsin A. This disease is due to mutations in the CTSA gene which encodes the protective protein cathepsin A PPCA This in turn