ⓘ NDFIP1

                                     

ⓘ NDFIP1

The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins.

                                     
  • family - interacting protein 2 is a protein that in humans is encoded by the NDFIP 2 gene. NDFIP 2 has been shown to interact with NEDD4. GRCh38: Ensembl release 89:
  • C19orf18 Result Summary BioGRID. NDFIP1 - NEDD4 family - interacting protein 1 - Homo sapiens Human - NDFIP1 gene protein UniProt. ACVR2A activin
  • tyrosine residues to activate NEDD4 ubiquitin ligase activity. The NDFIP1 and NDFIP 2 proteins function as adaptor proteins that can facilitate NEDD4 binding
  • Shearwin - Whyatt LM, Brown DL, Wylie FG, Stow JL, Kumar S 2005 N4WBP5A Ndfip 2 a Nedd4 - interacting protein, localizes to multivesicular bodies and the
  • vivo. NDFIP1 and NDFIP 2 proteins bind NEDD4 - 2 and regulate its activity and or interaction with substrates. NEDD4 - 2 phosphorylation by kinases SGK 1 and