ⓘ T-cell activation RhoGTPase activating protein

                                     

ⓘ T-cell activation RhoGTPase activating protein

This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

                                     
  • GTPase - activating proteins or GTPase - accelerating proteins GAPs are a family of regulatory proteins whose members can bind to activated G proteins and
  • Rho family of GTPases is a family of small 21 kDa signaling G proteins and is a subfamily of the Ras superfamily. The members of the Rho GTPase family
  • Rho GTPase activating protein 21 is a protein that in humans is encoded by the ARHGAP21 gene. ARHGAP21 functions preferentially as a GTPase - activating
  • RAS p21 protein activator 1 or RasGAP Ras GTPase activating protein also known as RASA1, is a 120 - kDa cytosolic human protein that provides two principal
  • Transforming protein Rho A, also known as Ras homolog family member A Rho A is a small GTPase protein in the Rho family of GTPases that in humans is encoded
  • response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision. Protein biosynthesis
  • Guanine nucleotide exchange factors GEFs are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate
  • G proteins also known as guanine nucleotide - binding proteins are a family of proteins that act as molecular switches inside cells and are involved
  • Rho - associated protein kinase ROCK is a kinase belonging to the AGC PKA PKG PKC family of serine - threonine kinases. It is involved mainly in regulating
  • ABR, Rho GEF and GTPase activating protein is a protein that in humans is encoded by the ABR gene. This gene encodes a protein that is similar to the protein
  • small 21 kDa signaling G protein to be specific, a GTPase and is a member of the Rnd subgroup of the Rho family of GTPases It is encoded by the gene
  • for GTP so as to promote subsequent Rho G - mediated signalling. The second class are known as GTPase activating proteins GAPs and these promote hydrolysis