ⓘ Ring finger protein 103

                                     

ⓘ Ring finger protein 103

The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment ECT as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 charged multivesicular body protein 3 gene.

                                     
  • In molecular biology, a RING Really Interesting New Gene finger domain is a protein structural domain of zinc finger type which contains a C3HC4 amino
  • neighboring RNF 103 ring finger protein 103 and CHMP3 charged multivesicular body protein 3 genes. The read - through transcript encodes a fusion protein that
  • least 60 different proteins involved in transcription, they are known to act as E3 SUMO - protein ligases. In essence, the RING - finger - like zinc - binding
  • Ring finger protein 43 is a protein that in humans is encoded by the RNF43 gene. The protein encoded by this gene is a RING - type E3 ubiquitin ligase and
  • ring finger protein 3 is a protein that in humans is encoded by the MKRN3 gene. The protein encoded by this gene contains a RING C3HC4 zinc finger motif
  • ubiquitin - protein ligase RLIM is an enzyme that in humans is encoded by the RLIM gene. The protein encoded by this gene is a RING - H2 zinc finger protein It
  • functions and in DNA repair. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with
  • group RING finger protein 6 is a protein that in humans is encoded by the PCGF6 gene. The protein encoded by this gene contains a RING finger motif
  • Interaction between human topoisomerase I and a novel RING finger arginine - serine protein Nucleic Acids Res. 27 12 2538 44. doi: 10.1093 nar 27
  • degradation E3, gp78, requires its Cue domain, RING finger and an E2 - binding site Proc. Natl. Acad. Sci. U.S.A. 103 2 341 6. doi: 10.1073 pnas.0506618103
  • motif - containing protein 5 also known as RING finger protein 88 is a protein that in humans is encoded by the TRIM5 gene. The alpha isoform of this protein TRIM5α