ⓘ Additional sex combs like 2, transcriptional regulator

                                     

ⓘ Additional sex combs like 2, transcriptional regulator

This gene encodes a member of a family of epigenetic regulators that bind various histone-modifying enzymes and are involved in the assembly of transcription factors at specific genomic loci. Naturally occurring mutations in this gene are associated with cancer in several tissue types. This gene plays an important role in neurodevelopment, cardiac function, adipogenesis, and osteoclastogenesis.

                                     
  • Randazzo F, Brock HW Mar 2003 A human homolog of Additional sex combs ADDITIONAL SEX COMBS - LIKE 1, maps to chromosome 20q11 Gene. 306: 115 26. doi: 10
  • Additional sex combs like 3 Drosophila is a protein that in humans is encoded by the ASXL3 gene. GRCh38: Ensembl release 89: ENSG00000141431 - Ensembl
  • Neuroendocrinology Paracrine signaling Plant hormones, a.k.a. plant growth regulators Semiochemical Sex - hormonal agent Sexual motivation and hormones Xenohormone Shuster
  • H 2 A with a single ubiquitin group H 2 AK119ub The Drosophila PRC1 core complex is formed by the Polycomb Pc Polyhomeotic Ph Posterior sex combs