ⓘ Β-lactam antibiotic

                                     

ⓘ Β-lactam antibiotic

β-lactam antibiotics are the antibiotic agents that contain a beta-lactam ring in their molecular structure. This includes penicillin derivatives, cephalosporins, monobactams, carbapenems and carbacephems. Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organism and are the most widely used group of antibiotics. Until 2003, when measured by sales, more than half of all commercially available antibiotics in use were β-lactam compounds. The first β-lactam antibiotic discovered, penicillin, was isolated from a rare variant of Penicillium notatum.

Bacteria often develop resistance to β-lactam antibiotics by synthesizing a β-lactamase, the enzyme that affects β the β-lactam ring. To overcome this resistance, β-lactam antibiotics are often given with inhibitors of β-lactamase, such as clavulanic acid.

                                     
  • list of common β - lactam antibiotics - both administered drugs and those not in clinical use - organized by structural class. Antibiotics are listed alphabetically
  • carbonyl. The simplest β - lactam possible is 2 - azetidinone. The β - lactam ring is part of the core structure of several antibiotic families, the principal
  • Tabtoxinine β - lactam is a monobactam antibiotic derived from tabtoxin. Unlike other β - lactam antibiotics which inhibit penicillin - binding proteins, tabtoxinine
  • ring size: α - Lactam 3 - atom rings β - Lactam 4 - atom rings γ - Lactam 5 - atom rings δ - Lactam 6 - atom rings ε - Lactam 7 - atom rings This ring - size nomenclature
  • an antibiotic It is effective for the treatment of urinary tract infections. It contains cefoperazone, a β - lactam antibiotic and sulbactam, a β - lactamase
  • antibiotic consisting of ticarcillin, a β - lactam antibiotic and clavulanic acid, a β - lactamase inhibitor. This combination results in an antibiotic with
  • Although β - lactamase inhibitors have little antibiotic activity of their own, they prevent bacterial degradation of beta - lactam antibiotics and thus extend
  • Methicillin, also known as meticillin, is a narrow - spectrum β - lactam antibiotic of the penicillin class. Meticillin was discovered in 1960. Compared to
  • EC 3.5.2.6 produced by bacteria that provide multi - resistance to β - lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems
  • certain antibiotics to make them less vulnerable to bacteria s antimicrobial resistance. Tazobactam is combined with the extended spectrum β - lactam antibiotic
  • cephalosporins sg. ˌsɛfələˈspɔːrɪn, ˌkɛ - - loʊ - are a class of β - lactam antibiotics originally derived from the fungus Acremonium, which was previously