ⓘ Acrosin binding protein

                                     

ⓘ Acrosin binding protein

The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon.

                                     
  • secondary binding protein between the spermatozoa and zona pellucida. Under the secondary binding protein hypothesis, acrosin could serve a role in binding to
  • inhibit the sperm protease acrosin Large amounts of protein C inhibitor circulate in the male reproductive organ as a plasma protein Either deficiency or
  • Zona pellucida sperm - binding protein 4, ZP - 4 or avilesine, named after its discoverer Manuel Aviles Sanchezis a protein that in humans is encoded by the
  • Serine protease inhibitor Kazal - type 2 also known as acrosin - trypsin inhibitor is a protein that in humans is encoded by the SPINK2 gene. Kazal - type serine
  • Zona pellucida sperm - binding protein 2 is a protein that in humans is encoded by the ZP2 gene. The zona pellucida is an extracellular matrix that surrounds
  • pellucida sperm - binding protein 3, also known as zona pellucida glycoprotein 3 Zp - 3 or the sperm receptor, is a ZP module - containing protein that in humans