ⓘ Emactuzumab

                                     

ⓘ Emactuzumab

Emactuzumab is a humanized monoclonal antibody directed against CSF-1R expressed on macrophages and has demonstrated a profound antitumor effect through interference with the CSF-1/CSF-1R axis, along with a manageable safety profile in patients with diffuse-type tenosynovial giant cell tumors

                                     
  • Jean - Pierre Blay, Jean - Yves Ruttinger, Dominik 2015 CSF1R inhibition with emactuzumab in locally advanced diffuse - type tenosynovial giant cell tumours of the
  • trials include : Pexidartinib, PLX7486, ARRY - 382, JNJ - 40346527, BLZ945, Emactuzumab AMG820, IMC - CS4. PD - 0360324 and MCS110 are CSF1 inhibitors Another
  • trials include Pexidartinib, PLX7486, ARRY - 382, JNJ - 40346527, BLZ945, Emactuzumab AMG820, IMC - CS4, MCS110, and Cabiralizumab. CSF1R inhibitors such as
  • mab humanized SLAMF7 Y multiple myeloma Elsilimomab mab mouse IL - 6 Emactuzumab mab humanized CSF1R cancer Emapalumab Gamifant mab human interferon gamma