ⓘ Tyrosine hydroxylase

                                     

ⓘ Tyrosine hydroxylase

Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L -tyrosine to L -3.4-dihydroxyphenylalanine. It does so using molecular oxygen, as well as iron and tetrahydrobiopterin as cofactors. L -DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine and epinephrine. Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene, and the enzyme is present in the central nervous system, peripheral sympathetic neurons and the adrenal medulla. Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases.

                                     
  • Tryptophan hydroxylase TPH is an enzyme EC 1.14.16.4 involved in the synthesis of the neurotransmitter serotonin. Tyrosine hydroxylase phenylalanine
  • acid hydroxylases AAAH are a family of aromatic amino acid hydroxylase enzymes which includes phenylalanine 4 - hydroxylase EC 1.14.16.1 tyrosine 3 - hydroxylase
  • Tyrosine N - monooxygenase EC 1.14.13.41, tyrosine N - hydroxylase CYP79A1 is an enzyme with systematic name L - tyrosine NADPH: oxygen oxidoreductase N - hydroxylating
  • Phenylalanine hydroxylase PAH EC 1.14.16.1 is an enzyme that catalyzes the hydroxylation of the aromatic side - chain of phenylalanine to generate tyrosine PAH
  • Alpha - methyl - p - tyrosine AMPT is a tyrosine hydroxylase enzyme inhibitor. Alpha - methyl - p - tyrosine AMPT is a non - endogenous drug involved in the catecholamine
  • sulfotyrosine. In dopaminergic cells in the brain, tyrosine is converted to L - DOPA by the enzyme tyrosine hydroxylase TH TH is the rate - limiting enzyme involved
  • molecule found in fungus metabolism. It is an inhibitor of the enzyme tyrosine hydroxylase Tsantrizos YS, Yang X, McClory A September 1999 Studies on the
  • 3 - diiodothyronine. 3 - Iodotyrosine is a reversible inhibitor of the enzyme tyrosine hydroxylase 3 - Iodotyrosine, a pathway inhibitor in the synthesis of the neurotransmitter
  • is an anthraquinone derivative. It is an inhibitor of the enzyme tyrosine hydroxylase Saquayamycins saquayamycins A, B, C and D are antibiotics of the
  • effects, WF - 11 has been shown to produce a uniform downregulation of tyrosine hydroxylase protein and activity gene expression with a regimen of use. List