ⓘ Regulatory macrophages

                                     

ⓘ Regulatory macrophages

Regulatory macrophages represent one of basic macrophage population according fundamental macrophage function. These functions are host defense, wound healing and immune regulation. Physiological role of Mregs is to dampen the immune response and limit immunopathology. Unlike classically activated macrophages, Mregs produce high levels of anti-inflammatory cytokine interleukin 10 and turn off IL-12 synthesis. And unlike wound-healing macrophages, Mregs do not induct arginase, so they do not contribute to the production of the extracellular matrix.

                                     
  • neoplasia. Moreover, macrophages infiltrating the tumor microenvironment can transition towards a regulatory phenotype. Regulatory macrophages produce Interleukin
  • classification, macrophage phenotype has been divided into 2 groups: M1 classically activated macrophages and M2 alternatively activated macrophages This
  • M1 macrophages wound - healing macrophages also known as alternatively - activated M2 macrophages and regulatory macrophages Mregs Macrophages that
  • cancer - related inflammation. Macrophages are known to originate from bone marrow - derived blood monocytes monocyte - derived macrophages or yolk sac progenitors
  • Signal regulatory protein α SIRPα is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or
  • effects of inflammatory cytokines on steroidogenic acute regulatory protein expression in macrophages Inflamm Res. 56 12 495 501. doi: 10.1007 s00011 - 007 - 6133 - 3
  • interferon - gamma activated macrophages Microb. Pathog. 39 3 57 67. doi: 10.1016 j.micpath.2005.05.001. hdl: 2429 15708. PMID 16084683. Macrophage - 1 antigen at the
  • Macrophage - capping protein CAPG also known as actin regulatory protein CAP - G is a protein that in humans is encoded by the CAPG gene. This gene encodes
  • switch that controls whether macrophages will promote or inhibit inflammation. Blocking the production of IRF5 in macrophages may help treat a wide range
  • cells alveolar macrophages which cause enzymes, complement proteins, and regulatory factors such as interleukin - 1 to get produced. The macrophages also carry
  • Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. IRF7 encodes interferon