ⓘ MIR1269A

                                     

ⓘ MIR1269A

microRNAs miRNAs are short 20-24 nt non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts pri-miRNAs that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA pre-miRNA, which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star miRNA* products. The mature miRNA is incorporated into a RNA-induced silencing complex RISC, which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

                                     
  • 2010 miR - 137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells Int J Cancer. 128 6 1269 79.
  • encoding protein Major facilitator superfamily domain containing 7 MIR1269A microRNA 1269 a MLF1IP: Centromere protein U MMAA: methylmalonic aciduria cobalamin
  • Farrukhsiyar had given Mir Jumla III the power to sign documents on his behalf: The word and seal of Mir Jumla are my word and seal Mir Jumla III began approving
  • Almohads Morocco, Ifriqiya, Central Maghreb and Al - Andalus, f. 1130, r. 1147 1269 Ayyubids Egypt, 1171 1341 Hafsid dynasty Ifriqiya, 1229 1574 Nasrid
  • Romania in Pitești NRJ Russia alternative frequency in St. Petersburg Radio MIR in Novosibirsk Class 95FM BBC Radio Gloucestershire 95 FM in Stroud Celtic
  • Panditacharya, author of Sumadhvavijaya, Sangraha Ramayana Vedanta Desika 1269 1370 Sri Vaishnava writer, poet, devotee, philosopher and teacher Krishnadevaraya
  • October Brian Conaghan, young adult fiction writer 7 October Aasmah Mir journalist and presenter 8 October Michelle Mone, entrepreneur 13 November
  • in 1263. The state lapsed into years of internal fighting. From 1263 to 1269 Lithuania had three grand dukes Treniota, Vaisvilkas, and Svarnas. The
  • Naqshbandi, and Suhrawardi orders. Khalil Ahmad was born in late Safar 1269 AH early December 1852 in Nanauta, Saharanpur district, British India in
  • Nawaz d. 1422 in Gulbarga, India Syed baqaullah shah kareemisafipur, unnao 1269 H1362H Akhi Siraj Aainae Hind d. 1357 in Bengal, IndiaAlaul Haq Pandavi