ⓘ Prophenoloxidase

                                     

ⓘ Prophenoloxidase

Prophenoloxidase is a modified form of the complement response found in some invertebrates, including insects, crabs and worms.

Primary innate defense system in invertebrates is mehanizacii of pathogens and damaged tissue. This important process is carried out by the enzyme phenoloxidase in. The conversion of prophenoloxidase to the active form of the enzyme can be caused by a small number of molecules, such as lipopolysaccharide, peptidoglycan and ß-1.3-glucans from microorganisms.

However, it still has many arguments in its innate immune function, particularly in the model invertebrates. Roller homologous protein in mammals also has no immune activity. Thus, it can be difficult to complete its function of immunity.

                                     
  • activation of the enzyme phenoloxidase PO which is controlled by the prophenoloxidase proPO activation system. During activation of proPO cascade, many
  • Retrieved 2 February 2017. Armigeres subalbatus Diptera: Culicidae prophenoloxidase III is required for mosquito cuticle formation: ultrastructural study
  • bacteria indirectly by activating one of four unique effector pathways: prophenoloxidase cascade, activation of Toll pathway, activation of IMD pathway, and
  • laminarin and bacterial lipopolysaccharide - induced activation of the prophenoloxidase cascade in the African migratory locust Locusta migratoria. Journal
  • Swansea University in 1988. Nigam s doctoral research investigated the prophenoloxidase system pPO in reduviid bugs and tsetse flies using in vitro experiments
  • cascade, the complement system, apoptosis pathways, and the invertebrate prophenoloxidase - activating cascade Proteases can either break specific peptide bonds