ⓘ Innate lymphoid cell

                                     

ⓘ Innate lymphoid cell

Innate lymphoid cells are a group of innate immune cells that are derived from common lymphoid progenitors and belong to the lymphoid lineage. These cells are defined by absence of antigen specific B or T cell receptor because of the lack of recombination activating gene. ILCs do not express myeloid or dendritic cell markers.

This relatively newly described group of cells have different physiological functions, some functions similar to the T-helper cells, while the group also includes NK cells and cytotoxic. Accordingly, they play an important role in protective immunity and regulation of homeostasis and inflammation, so their violation can lead to immune pathologies such as allergies, asthma and autoimmune diseases. In addition, they can regulate adipose function and metabolic homeostasis, in particular, to provoke Beijing.

                                     
  • Type 3 innate lymphoid cells ILC3 are lymphoid line immune cells and are one of the classified type of Innate lymphoid cells Due to their functions
  • ILC2 cells or type 2 innate lymphoid cells are a type of innate lymphoid cell They are derived from common lymphoid progenitor and belong to the lymphoid
  • cell in a vertebrate s immune system. Lymphocytes include natural killer cells which function in cell - mediated, cytotoxic innate immunity T cells for
  • insects, and involves the production of methyl jasmonate. Apoptosis Innate lymphoid cell NOD - like receptor Janeway C, Travers P, Walport M, Shlomchik M 2001
  • factor RORα is critical for nuocyte development Nature Immunology. 13 3 229 36. doi: 10.1038 ni.2208. PMC 3343633. PMID 22267218. Innate lymphoid cell
  • and destroyed by other immune cells such as T lymphocyte cells NK cells belonging to the group of innate lymphoid cells are defined as large granular
  • interleukin - 33 - mediated group 2 innate lymphoid cell activation, 2 how interferons regulate group 1 and 2 innate lymphoid cell functions, and 3 mechanisms
  • of the lymphoid parts of all secondary lymphoid organs. In the B cell follicles, the macrophages are important in clearing the apoptotic B cells that occur
  • role in allergic asthma led to his discovery of type - 2 innate lymphoid cells ILC2 These cells secrete large quantities of cytokines and represent a
  • lymphocytes, one of the five types of white blood cell WBC It is more formally known as lymphoid hematopoiesis. Pathosis in lymphopoiesis leads to