ⓘ Epimerox

                                     

ⓘ Epimerox

Epimerox is an experimental broad-spectrum antibiotic compound being developed by scientists at the Rockefeller University and Astex Pharmaceuticals. It is a small molecule inhibitor compound that blocks the activity of the enzyme UDP- N -acetylglucosamine 2-epimerase, an epimerase enzyme that is called 2-epimerase for short.

                                     
  • UDP - N - acetylglucosamine 2 - epimerase, the target of the experimental antibiotic epimerox UDP - N - acetylglucosamine 2 - epimerase hydrolysing UDP - N, N - diacetylbacillosamine
  • capsule precursor UDP - ManNAcA. An inhibitor of the bacterial 2 - epimerase, epimerox has been described. Some of these enzymes are bifunctional. The UDP - N - acetylglucosamine