ⓘ Trichohyalin

                                     

ⓘ Trichohyalin

In 1903 the name" trichohyalin” was assigned to the granules of the inner root sheath IRS of hair follicles discovered by H. Voerner. In 1986 the name was reassigned to a protein isolated from sheep wool follicles.

                                     
  • family NOS EC 1.14.13.39 It is made from arginine by the enzyme trichohyalin at the inner root sheath and medulla of hair follicles. Arginine is first
  • filaggrin - like proteins. filaggrin FLG filaggrin - 2 FLG2 trichohyalin TCHH trichohyalin - like 1 TCHHL1 cornulin CRNN repetin RPTN hornerin HRNR
  • PMID 9326318. Tarcsa E, Marekov LN, Andreoli J, et al. 1997 The fate of trichohyalin Sequential post - translational modifications by peptidyl - arginine deiminase
  • Medland SE, Nyholt DR, Painter JN, et al. 2009 Common variants in the trichohyalin gene are associated with straight hair in Europeans Am. J. Hum. Genet
  • hyperproliferation of inner root sheath cells containing large eosinophilic trichohyalin granules. Antibodies against major capsid protein VP1, the major component
  • Medland SE, Nyholt DR, Painter JN, et al. 2009 Common variants in the trichohyalin gene are associated with straight hair in Europeans Am. J. Hum. Genet
  • hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with