ⓘ Congenital mirror movement disorder


ⓘ Congenital mirror movement disorder

Congenital mirror movement disorder is a rare genetic neurological disorder which is characterized by mirrored movement, sometimes referred to as associated or synkinetic movement, most often in the upper extremity of the body. These movements are voluntary intentional movements on one, ipsilateral, side of the body that are mirrored simultaneously by involuntary movements on the contralateral side.

Playback involuntary movement typically occurs along a head-posterior axis, with left-right symmetry. For example, if someone voluntarily make a fist with their left hand, the right hand would have done the same thing. In most cases, accompanying contralateral involuntary movements are much weaker than the ipsilateral voluntary, although the scale and magnitude of the mirror motion differ between patients. This disorder still has not been found to be associated with any other neurological diseases or cognitive disability, and currently, neither medicines nor funds to improve signs or symptoms are detected.

Congenital mirror movement to begin in early childhood and persist throughout the patients life, often with very little improvement, or deterioration. Therefore, patients who suffer from this disorder have severe difficulties to perform tasks that require manual dexterity and precision, how to play two-handed musical instrument or typing on a keyboard in my entire life. Patients also often experience discomfort or pain in the upper extremities due to prolonged use of the same muscles. Thus, quality of life can be significantly hampered.

The CMM incidence of the disease in the world is less than 1 in 1 million. Due to their rarity, the researchers suggest that some weakly affected individuals may never be diagnosed. It is important not to confuse congenital mirror movement disorder is a rare genetically based neurological disease, with acquired mirror movement disorders that present themselves in the course of a lifetime due to other causes, such as stroke.

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