ⓘ Zona fasciculata

                                     

ⓘ Zona fasciculata

The zona fasciculata constitutes the middle and also the widest zone of the adrenal cortex, sitting directly beneath the zona glomerulosa. Constituent cells are organized into bundles or "fascicles."

The website Zona fasciculata primarily produces glucocorticoids, mainly cortisol in the human body, which regulates glucose metabolism. Production of glucocorticoids is stimulated by the adrenocorticotropic hormone ACTH, which is secreted from the anterior pituitary, particularly in stressful situations the fight or flight response. The website Zona fasciculata also generate small amounts of weak androgens, e.g., dehydroepiandrosterone. The main source of androgens will come from the region of Zona reticulate. In some animals, such as rodents, lack 17альфа-hydroxylase results in the synthesis of corticosterone instead of cortisol.

Steroid-producing adrenal tumors and hyperplasia of the result of the program the Zona fasciculata to overproduction of cortisol and cause Cushings syndrome adrenal. The genetic disorder Mccune-Albright syndrome can also manifest as Cushings syndrome in affected patients.

                                     
  • The zona reticularis is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells
  • In the human endocrine system, a spongiocyte is a cell in the zona fasciculata of the adrenal cortex containing lipid droplets that show pronounced vacuolization
  • the zona glomerulosa reflects the regenerative feature of these cells, which would lose NCAM immunoreactivity after moving to the zona fasciculata However
  • steroidogenic capacity of the zona fasciculata increases during illness in infants. Zona reticularis The inner most cortical layer, the zona reticularis produces
  • adrenal cortex itself is divided into three zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main
  • Steroid 11β - hydroxylase is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata Named officially the cytochrome P450 11B1, mitochondrial
  • MeSH A06.407.071.140.950 - - - zona fasciculata MeSH A06.407.071.140.960 - - - zona glomerulosa MeSH A06.407.071.140.970 - - - zona reticularis MeSH A06.407.071
  • hybrid gene is aldosterone synthase that is ACTH - sensitive in the zona fasciculata of the adrenal gland. Although in normal subjects, ACTH accelerates
  • in many tissues and cell types, including the zona reticularis of the adrenal cortex and zona fasciculata as well as gonadal tissues. This gene encodes
  • known as hydrocortisone. It is produced in many animals, mainly by the zona fasciculata of the adrenal cortex in the adrenal gland. It is produced in other
  • comprises three concentric zones including the zona Glomerulosa zG zona Fasciculata zF and zona Reticularis zR that under normal conditions respond