ⓘ MiR-146

                                     

ⓘ MiR-146

miR-146 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference.

Mir-146 is primarily involved in the regulation of inflammation and other processes that function in the immune system. The loss of function of Mir-146 and miR-145 may predispose the individual to suffer from chromosome 5B syndrome deletion. Mir-146 has also been reported to be highly upregulated in osteoarthritis cartilage, and may be involved in pathogenesis. Mir-146 expression is associated with survival in triple-negative breast cancer.

                                     
  • MicroRNA 146 a is a small non - coding RNA that in humans is encoded by the MIR 146 A gene. microRNAs mi RNAs are short 20 - 24 nt non - coding RNAs that are
  • The Martin Model 146 was an unsuccessful American bomber design that lost a 1934 1935 bomber design competition to the prototype for the Douglas B - 18
  • Route 146 is a limited - access road in the U.S. state of Rhode Island, maintained by the Rhode Island Department of Transportation RIDOT Spanning approximately
  • State Route 146 SR 146 is a state highway in the U.S. state of California in Monterey and San Benito Counties. The route serves as an entryway to Pinnacles
  • MiR - 155 is a microRNA that in humans is encoded by the MIR 155 host gene or MIR 155HG. MiR - 155 plays a role in various physiological and pathological processes
  • reduction of tumor growth. Sonkoly et al. identified miR - 203, along with miR - 146 a, miR - 21, and miR - 125b as a psoriasis - specific microRNA when compared
  • UFC 146 dos Santos vs. Mir was a mixed martial arts MMA pay - per - view event PPV promoted by the Ultimate Fighting Championship UFC on May 26, 2012
  • The Caproni Ca. 146 was a high - wing reconnaissance aircraft built by Caproni in the mid - 1930s. The Ca. 146 was a derivative of the Ca.127, and was similar
  • MicroRNA - 223 miR - 223 is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. miR - 223 is a hematopoietic
  • German submarine U - 146 was a Type IID U - boat of Nazi Germany s Kriegsmarineduring World War II. Her keel was laid down on 30 March 1940 by Deutsche Werke
  • PK, Szeto CC May 2012 Glomerular and tubulointerstitial miR - 638, miR - 198 and miR - 146 a expression in lupus nephritis Nephrology. 17 4 346 51.