ⓘ Charles A. Dinarello


ⓘ Charles A. Dinarello

Charles A. Dinarello is a professor of medicine currently at the University of Colorado at Denver. He is an expert on inflammatory cytokines, specifically Interleukin 1.

Dinarello received his Doctor of Medicine in 1969 at Yale University and since 1996, he is Professor of Medicine at University of Colorado School of Medicine. He is also Professor of Experimental Medicine at the Radboud University Medical Center in Nijmegen, The Netherlands. Dinarello is considered one of the founding fathers of cytokines having purified and cloned interleukin-1. This important step established the validation of cytokines as mediators of disease, particularly of inflammation. Current studies blocking IL-1 in humans supports Dinarellos and his co-workers pivotal contributions to cytokine biology and the pathogenesis of inflammatory diseases.

He is fluent in English, Italian and German.


1. Awards

  • The 2009 Albany Medical Center Prize Shared with Ralph M. Steinman and Bruce A. Beutler
  • 2010: Paul Ehrlich and Ludwig Darmstaedter Prize
  • 1993, Ernst Jung Prize
  • 2006, Hamdan Award for Medical Research Excellence, awarded by Sheikh Hamdan bin Rashid Al Maktoum Award for Medical Sciences, Dubai, United Arab Emirates
  • 2009, together with Tadamitsu Kishimoto and Toshio Hirano: Crafoord Prize in Polyarthritis;" for their pioneering work to isolate interleukins, determine their properties and explore their role in the onset of inflammatory diseases”.
  • 2011: Foreign membership of the Royal Netherlands Academy of Arts and Sciences
  • 2010: Novartis Prize in Clinical Immunology together with Juerg Tschopp.
  • 2009: Press Release Bruce A. Beutler Charles A. Dinarello Ralph M. Steinman 2008: Press Release Joan A Steitz Elizabeth Blackburn 2007: Press Release
  • research on interleukin - 1 IL - 1 and his collaboration with Dr. Charles A Dinarello to find out whether this was an IL - 1 disease. In the early 1990s
  • Francisco Carol W. Greider, Johns Hopkins University, Baltimore 2010 Charles Dinarello University of Colorado Denver 2011 Cesare Montecucco, University
  • Prize 2009, shared with Charles A Dinarello and Ralph M. Steinman Balzan Prize for Innate Immunity 2007, shared with Jules A Hoffmann Doctor of Medicine
  • PMID 18283340. Reddy, Pavan Koreth, John Dinarello Charles A Lewis, Eli C. Choi, Sung Won Yanik, Gregory A Parkin, Brian L. Alyea, Edwin P. Ho
  • Dies Expert in Infectious Diseases and High Fevers NY Times. Dinarello Charles A 2015 The history of fever, leukocytic pyrogen and interleukin - 1
  • Neurological Disorders Hamdan Award for Medical Research Excellence: Charles A Dinarello US - Biology of Aging Prof. Christian Hass Germany - Cytokines
  • ISSN 0022 - 1767. PMID 19717512. Dinarello Charles A 2004 - 03 - 01 Unraveling the NALP - 3 IL - 1β Inflammasome: A Big Lesson from a Small Mutation Immunity
  • and microbes programme at the Wellcome Sanger Institute in Cambridge and a Professor of Genomics at the University of Oxford. Kwiatkowski applies genomics
  • Tania Netea, Mihai G. Joosten, Leo A B. van der Meer, Jos W. M. Hao, Ruyi Kalabokis, Vassili Dinarello Charles A 2012 - 02 - 21 IL - 38 binds to the