ⓘ TMEM126A

                                     

ⓘ TMEM126A

Transmembrane protein 126A is a mitochondrial transmembrane protein of unknown function coded for by the TMEM126A gene.

Nonsense mutation in TMEM126A gene has been shown to be associated with atrophy of the optic nerve. TMEM126A shows higher levels of expression in the parathyroid gland and in peripheral blood cells of patients with Huntingtons disease, indicating that the expression of this protein has any relevance to the regulation of blood.

TMEM126A has two isoforms and is located on the long arm of chromosome 11 in region 1, Band 4, subband 1. It is produced TMEM126 the gene that encodes the mRNA of 726 base pairs. which means a protein of 195 amino acids. In addition, this gene is expressed 1.8 times the average normal gene and expression from the prostate, uterus, kidney, placenta, heart, brain and many other tissues.

                                     
  • member of the membrane - associated guanylate kinase family. TMEM126A A paralog of TMEM 126 B expressed in the mitochondria. CREBZF: Also known as the Zhangfei
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  • superfamily member 2 TMEM 109: encoding protein Transmembrane protein 109 TMEM 123: transmembrane protein 123 TMEM 126 B: transmembrane protein 126 B TMEM 134: transmembrane
  • TIMMDC1 associates reciprocally with multiple components of the ECSIT - TMEM 126 B - ACAD9 - NDUFAF1 assembly factor complex MCIA complex GRCh38: Ensembl
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  • mitochondrial complex I assembly MCIA complex. The complex comprises at least TMEM 126 B, NDUFAF1, ECSIT, and ACAD9, which interacts directly with NDUFAF1 and
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  • PMID 9058802. Li Q, Lan X, Han X, Wang J January 2019 Expression of Tmem 119 Sall1 and Ccr2 CD69 in FACS - Sorted Microglia - and Monocyte Macrophage - Enriched
  • thyroglobulin THAP1: THAP domain containing, apoptosis associated protein 1 TMEM 67: encoding protein Meckelin TNFRSF11B: tumor necrosis factor receptor superfamily