ⓘ Trypsin

                                     

ⓘ Trypsin

Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins. Trypsin is formed in the small intestine when its proenzyme form, the trypsinogen produced by the pancreas, is activated. Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine. It is used for numerous biotechnological processes. The process is commonly referred to as trypsin proteolysis or trypsinisation, and proteins that have been digested/treated with trypsin are said to have been trypsinized. Trypsin was discovered in 1876 by Wilhelm Kuhne and was named from the Ancient Greek word for rubbing since it was first isolated by rubbing the pancreas with glycerin.

                                     
  • A trypsin inhibitor TI is a protein and a type of serine protease inhibitor serpin that reduces the biological activity of trypsin by controlling the
  • Trypsin - 1, also known as cationic trypsinogen, is a protein that in humans is encoded by the PRSS1 gene. Trypsin - 1 is the main isoform of trypsinogen secreted
  • pancreatic trypsin inhibitor BPTI or basic trypsin inhibitor of bovine pancreas, which is an antifibrinolytic molecule that inhibits trypsin and related
  • Sunflower trypsin inhibitor is Sunflower trypsin inhibitor SFTI - 1 Sunflower trypsin inhibitor - 1 is a potent Bowman - Birk inhibitor. Sunflower trypsin inhibitor - 1
  • Inter - alpha - trypsin inhibitors IαI are plasma proteins consisting of three of four heavy chains selected from the group ITIH1, ITIH2, ITIH3, ITIH4 and
  • soybean trypsin inhibitor is a type of protein contained in legume seeds which functions as a protease inhibitor. Kunitz - type Soybean Trypsin Inhibitors
  • serine, 2 trypsin 2 is a protein that in humans is encoded by the PRSS2 gene. This gene encodes a trypsinogen, which is a member of the trypsin family of
  • into two broad categories based on their structure: chymotrypsin - like trypsin - like or subtilisin - like. The MEROPS protease classification system counts
  • Pancreatic secretory trypsin inhibitor PSTI also known as serine protease inhibitor Kazal - type 1 SPINK1 or tumor - associated trypsin inhibitor TATI is
  • the intestinal mucosa, to form trypsin Once activated, the trypsin can activate more trypsinogen into trypsin Trypsin cleaves the peptide bond on the
  • Inter - alpha - trypsin inhibitor heavy chain H2 is a protein that in humans is encoded by the ITIH2 gene. It is known to contain a Gla domain, and thus be