ⓘ Thin basement membrane disease

                                     

ⓘ Thin basement membrane disease

Thin basement membrane disease is, along with IgA nephropathy, the most common cause of hematuria without other symptoms. The only abnormal finding in this disease is a thinning of the basement membrane of the glomeruli in the kidneys. Its importance lies in the fact that it has a benign prognosis, with patients maintaining a normal kidney function throughout their lives.

                                     
  • The basement membrane is a thin fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying
  • overlap with chronic pelvic pain syndrome. A thin glomerular basement membrane as in thin basement membrane disease is proposed to be the characteristic finding
  • hereditary glomerulonephropathy and with familial benign hematuria thin basement membrane disease Two transcripts, differing only in their transcription start
  • the world. Thin basement membrane disease is an autosomal dominant inherited disease characterized by thin glomerular basement membranes on electron
  • epithelium is connected to a basement membrane which is then attached by filaments to a connective tissue layer. The chorionic membrane is a fibrous tissue layer
  • characteristic sequence of changes from thinning of the glomerular basement membrane GBM developing into areas of thinning and thickening, and finally into
  • the alveolar wall, the endothelial cells of the capillaries and the basement membrane between the two cells. The barrier is permeable to molecular oxygen
  • Benedek Descemet s membrane also posterior limiting membrane a thin acellular layer that serves as the modified basement membrane of the corneal endothelium
  • and its basement membrane a thin interstitial space between the epithelial lining and the capillary membrane a capillary basement membrane that often
  • COL4A3 gene. Type IV collagen, the major structural component of basement membranes is a multimeric protein composed of 3 alpha subunits. These subunits