ⓘ SESN1

                                     

ⓘ SESN1

Sestrin 1, also known as p53-regulated protein PA26, is a protein that in humans is encoded by the SESN1 gene. This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

                                     
  • produce rapid - acting antidepressant effects similar to those of ketamine. SESN1 ENSG00000285069 GRCh38: Ensembl release 89: ENSG00000130766, ENSG00000285069
  • PA26 may refer to: Pennsylvania Route 26 Pennsylvania s 26th congressional district SESN1 a protein
  • Sestrin 3 is a protein that in humans is encoded by the SESN 3 gene. This gene encodes a member of the sestrin family of stress - induced proteins. The encoded
  • and the future is uncertain. RRC airs several Rossland - based shows, like Sesn - a - tonin, as well as a few syndicated programs, like Pacifica Radio s Democracy
  • ISSN 0511 - 5728. Retrieved 20 January 2020. Prof. C.O. Folayan, Vice - President sesn - ng.com. Retrieved 18 January 2020. NSE Membership Portal - Engr. Prof. Clement
  • T - cells 1 SBF2: SET binding factor 2 SCGB 1 D2: secretoglobin family 1 D member 2 SESN 3 encoding protein Sestrin 3 SIDT2 encoding protein SID 1 transmembrane
  • Kumar, A and Shaha, C SESN 2 facilitates mitophagy by helping Parkin translocation through ULK 1 mediated Beclin 1 phosphorylation. Scientific reports
  • HPS6, HPS7, AP3B 1 Hereditary neuropathy with liability to pressure palsies HNPP PMP22 Heterotaxy NODAL, NKX2 - 5, ZIC3, CCDC11, CFC 1 SESN1 Homocystinuria