ⓘ Autophagy-related protein 101

                                     

ⓘ Autophagy-related protein 101

Autophagy-related protein 101 also known as ATG101 is a protein that in humans is encoded by the C12orf44 gene.

Autophagy is a process of forming a vacuole around proteins and nucleic acids, which must be broken down in the lysosomes. The transcribed sequence of mRNA base pairs C12orf44 is 1287, and after the transfer of the sequence of 218 amino acids in length. In ATG101 protein is localized in the cytoplasm, but can also be found bound to the structure known as the phagophore involved in autophagy. The gene is highly conserved among mammals, and also shows the conservation of most eukaryotes. It is believed that directly interact with ATG13 in ULK1 complex, which can be important for the activation of phagophores.

                                     
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  • encoding protein Actin - related protein 2 3 complex subunit 3 Asun: encoding protein Protein asunder homolog Asun ATG 101 Autophagy - related protein 101 BCAT1: