ⓘ Schnyder crystalline corneal dystrophy

                                     

ⓘ Schnyder crystalline corneal dystrophy

Schnyder crystalline corneal dystrophy is a rare form of corneal dystrophy. It is caused by heterozygous mutations in UBIAD1 gene. Cells in the cornea accumulate cholesterol and phosopholipid deposits leading to the opacity, in severe cases requiring corneal transplants. Abnormal cholesterol metabolism has been noted in other cell types of affected patients suggesting that this may be a systemic disorder with clinical manifestations limited to the cornea.

                                     
  • lattice corneal dystrophy Granular corneal dystrophy type 1 Granular corneal dystrophy type 2 Macular corneal dystrophy Schnyder crystalline corneal dystrophy
  • oxidative stress pathways. Mutations of the UBIAD1 gene cause Schnyder crystalline corneal dystrophy GRCh38: Ensembl release 89: ENSG00000120942 - Ensembl
  • or SCD may refer to: Salicylate decarboxylase, an enzyme Schnyder crystalline corneal dystrophy an eye disease Sequential compression device, an inflatable