ⓘ TMEM18

                                     

ⓘ TMEM18

TMEM18 seems to affect energy levels through insulin and glucagon signaling, and in flies, its downregulation induces a metabolic state resembling type-II diabetes

Overexpression of TMEM18 protein increases the migration ability of neural stem cells during inactivation results TMEM18 in an almost complete loss of migration activity.

TMEM18 gene is obviously expressed in both mammalian and fly cells, which allows to speak about the basic cellular functions. In the mouse brain, it is found in most all cells, but more neurons than other cell types.