ⓘ CD8

                                     

ⓘ CD8

CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor. Like the TCR, CD8 binds to a major histocompatibility complex molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. In humans, both genes are located on chromosome 2 in position 2p12.

                                     
  • CD 8 a Cluster of Differentiation 8 a is a human gene. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates
  • The CD 4 CD8 ratio is the ratio of T helper cells with the surface marker CD 4 to cytotoxic T cells with the surface marker CD8 The CD 4 CD8 ratio
  • known as TC, cytotoxic T lymphocyte, CTL, T - killer cell, cytolytic T cell, CD8 T - cell or killer T cell is a T lymphocyte a type of white blood cell
  • to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD 4 cells become depleted, for example in untreated
  • many immune cells white blood cells including CD 4 CD8 B lymphocytes and natural killer cells. CD 38 also functions in cell adhesion, signal transduction
  • also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively
  • CD 4 coreceptor. This model was created to examine role of coreceptor coupling to Lck lymphocyte - specific protein tyrosine kinase as the CD 4 and CD8
  • the CD 3 cluster of differentiation 3 T cell co - receptor helps to activate both the cytotoxic T cell CD8 naive T cells and also T helper cells CD 4
  • CD8 cell noncytotoxic anti - HIV response appears to be an anti - HIV innate immune response because it can be observed in vitro with CD8 cells from unexposed
  • human CD 4 - CD8 - cytolytic T lymphocytes Nature. 341 6241 447 50. doi: 10.1038 341447a0. PMID 2477705. Zajonc DM, Wilson IA 2007 Architecture of CD 1 proteins