ⓘ CYP2A7

                                     

ⓘ CYP2A7

CYP2A7 is a protein that in humans is encoded by the CYP2A7 gene.

This gene encodes a member of cytochrome P450 superfamily of enzymes. Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein is localized in the endoplasmic reticulum, its substrate has not yet been determined. This gene, which produces two versions of the transcript is part of a large cluster of cytochrome P450 genes of the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

                                     
  • CR 1995 Expression and alternative splicing of the cytochrome P - 450 CYP2A7 Biochem. J. 306. Pt 1 161 6. PMC 1136496. PMID 7864805. Hoffman SM
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