ⓘ Interleukin 3

                                     

ⓘ Interleukin 3

Interleukin 3 is a protein that in humans is encoded by the IL3 gene localised on chromosome 5q31.1.

Synonyms: colony-stimulating factor, a growth factor of mast cells, multi-CSF, MCGF, MGC79398, MGC79399.

Protein contains 152 amino acids and its molecular mass is 17 KDA.

Il-3 is produced as a monomer on the activated T-cells, monocytes / macrophages and stroma cells.

                                     
  • Interleukins ILs are a group of cytokines secreted proteins and signal molecules that were first seen to be expressed by white blood cells leukocytes
  • The interleukin - 3 receptor CD123 is a molecule found on cells which helps transmit the signal of interleukin - 3 a soluble cytokine important in the immune
  • families of Interleukin receptors, Type 1 and Type 2. Type 1 interleukin receptors include: Interleukin - 1 receptor Interleukin - 2 receptor Interleukin - 3 receptor
  • Interleukin 5 IL5 is an interleukin produced by type - 2 T helper cells and mast cells. Through binding to the interleukin - 5 receptor, interleukin 5 stimulates
  • Interleukin 19 IL19 is a protein that in humans is encoded by the IL19 gene on the chromosome 1. The IL - 19 gene contains 7 exons and is found on chromosome
  • Interleukin 7 IL - 7 is a protein that in humans is encoded by the IL7 gene. IL - 7 is a hematopoietic growth factor secreted by stromal cells in the bone
  • Interleukin 20 IL20 is a protein that in humans is encoded by the IL20 gene. Interkeukin 20 also includes other cytokines, including IL - 19, IL - 20, IL - 22
  • Pro - interleukin - 16 is a protein that in humans is encoded by the IL16 gene. This gene was discovered in 1982 at Boston University by Dr. David Center
  • The interleukin 4 IL4, IL - 4 is a cytokine that induces differentiation of naive helper T cells Th0 cells to Th2 cells. Upon activation by IL - 4, Th2