ⓘ HHAT

                                     

ⓘ HHAT

Hedgehog acyltransferase, also called skinny hedgehog homology in humans, is a human gene.

HHAT gene encodes an enzyme that catalyzes that often plays a regulatory role of the N-terminal of Sonic hedgehog. Mutations in HHAT produce a phenotype that is similar to loss of function, hedgehog. Finally the HHAT protein shares a short but significant sequence similarity to membrane-bound o-acyltransferases.

                                     
  • 2010, HHAT was known to play a role in the sonic hedgehog pathway. When HHAT contains a loss - of - function mutation, less HHAT protein is produced. HHAT is
  • histidine residue of DltB MBOAT located at the bottom of the funnel. DGAT1 GUP1 HHAT HHATL LPCAT3 MBOAT1 MBOAT2 MBOAT4 MBOAT7 PORCN SOAT1 SOAT2 Hofmann K March
  • qawl Abī Rāʾita l - Takrītī al - Suryānī usquf Nasībīn mustadillan bihi ʿalā si hhat al - Nasr āniyya l - maqbūla min al - dāʿīn al - mubashshirīn bihā bi - l - Injīl al - muqaddas
  • membrane - bound O - acyltransferase family, Protein - cysteine N - palmitoyltransferase, HHAT A potential inhibitor of the Hedgehog signaling pathway has been found and
  • in cancer stem cell coordination and disease invasiveness and metastasis. Hhat inhibitors such as RU - SKI 43 block the Sonic hedgehog signaling pathway