ⓘ Neuromuscular junction disease
In diseases such as myasthenia gravis, the end plate potential EPP fails to effectively activate the muscle fiber due to an autoimmune reaction against acetylcholine receptors, resulting in muscle weakness and fatigue.
Myasthenia gravis occurs most often in auto-antibodies against acetylcholine receptors. He recently realized that a second category of gravis due to autoantibodies against the musk. Another condition Lambert–Eaton myasthenic syndrome, usually associated with antibodies to the presynaptic potential-dependent calcium channels. It is possible for these conditions to coexist.
- A neuromuscular junction or myoneural junction is a chemical synapse formed by the contact between a motor neuron and a muscle fiber. It is at the neuromuscular
- muscle, or indirectly, being pathologies of nerves or neuromuscular junctions Neuromuscular diseases are those that affect the muscles and their direct
- stimulations, a physician can assess for the presence of a neuromuscular junction disease and differentiate between presynaptic and postsynaptic conditions
- Kirstie Fields, of Llanelli. Fields disease is a neuromuscular disease causing muscular degeneration. The disease was first noticed when the twins were
- Encephalopathy Myelopathy Radiculopathy Neuromuscular junction disease Myopathy See also Charcot Marie Tooth disease Neuropathia mucinosa cutanea Neuropathic
- by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction They are called end plates because the postsynaptic terminals
- tyrosine kinase required for the formation and maintenance of the neuromuscular junction It is activated by a nerve - derived proteoglycan called agrin. Upon
- distinguish it from myasthenia gravis, a related autoimmune neuromuscular disease If the disease is associated with cancer, direct treatment of the cancer
- 2006. Retrieved 10 February 2007. Diseases of the Peripheral Nerve and Neuromuscular Junction Degenerative Diseases The Merck Veterinary Manual. 2006
- is an inherited neuromuscular disorder caused by defects of several types at the neuromuscular junction The effects of the disease are similar to Lambert - Eaton