ⓘ FBXO6

                                     

ⓘ FBXO6

F-box only protein 6 is a protein that in humans is encoded by the FBXO6 gene.

This gene encodes a member of f-box family protein, which is characterized by an approximately 40 amino acid sequence, f-field. F-box proteins are one of four subunits of the ubiquitin ligase protein complex, called the SCF, SKP1-Callen-f-box, which function in phosphorylation-dependent ubiquitination. F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, from the FBI, containing leucine-rich repeats, and Fbxs containing different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is very similar to the NFB42 rat neural F box 42 KDA that could be involved in the control of the cell cycle.