ⓘ DEFB105A

                                     

ⓘ DEFB105A

Beta-defensin 105 is a protein that is encoded by the DEFB105A gene in humans.

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by composition into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copies.

                                     
  • the HBD2 in 1997. DEFB 1 DEFB 103A DEFB105A DEFB 105 B DEFB 106 DEFB 108B DEFB 109 DEFB 110 DEFB 111 DEFB 114 DEFB 130 DEFB 136 DEFB 4 SPAG11A Defensin