ⓘ GSTO2

                                     

ⓘ GSTO2

Model organisms have been used in the study of GSTO2 function. A conditional knockout mouse line called Gsto2 tm2aKOMPWtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

                                     
  • PMID 15623683. Ozturk A, Desai PP, Minster RL, et al. 2005 Three SNPs in the GSTO 1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age - at - onset
  • PMID 15855271. Ozturk A, Desai PP, Minster RL, et al. 2005 Three SNPs in the GSTO 1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age - at - onset
  • stress, while glucagon decreases such gene expression. Omega - class GST GSTO genes, in particular, are associated with neurological diseases such as
  • GDAP1 GSTA1 GSTA 2 GSTA3 GSTA4 GSTA5 GSTM1 GSTM 2 GSTM3 GSTM4 GSTM5 GSTO 1 GSTP1 GSTT1 GSTT 2 GSTZ1 MARS PGDS PTGDS 2 PTGES 2 VARS Armstrong
  • al. published a paper revealing that glutathione S - transferase omega - 1 GSTO 1 modifies the age - at - onset AAO of Alzheimer disease AD and PD. In May