ⓘ SCGB1D2

                                     

ⓘ SCGB1D2

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.

SCGB1D2 expression is high in mammary tissue, and sometimes is used for identification and detection of disseminated breast cancer cells.

                                     
  • Secretoglobin family 3A member 1 is a protein that in humans is encoded by the SCGB 3A 1 gene. GRCh38: Ensembl release 89: ENSG00000161055 - Ensembl, May
  • also known as secretoglobin family 2 A member 1 is a protein that in humans is encoded by the SCGB 2 A 1 gene. SCGB 2 A 1 expression is highly specific of mammary
  • also known as secretoglobin family 2 A member 2 is a protein that in humans is encoded by the SCGB 2 A 2 gene. SCGB 2 A 2 is a member of the superfamily of secretoglobins
  • Secretoglobin family 3A member 2 is a protein that in humans is encoded by the SCGB 3A 2 gene. In addition to regulating thyroid - specific expression of
  • known as secretoglobin family 1 A member 1 SCGB 1 A 1 is a protein that in humans is encoded by the SCGB 1 A 1 gene. SCGB 1 A 1 is the founding member of the
  • T - cells 1 SBF 2 SET binding factor 2 SCGB1D2 secretoglobin family 1 D member 2 SESN3 encoding protein Sestrin 3 SIDT 2 encoding protein SID 1 transmembrane
  • HOXB5, SCGB 3A 1 and CRABP 1 as novel targets Molecular Cancer. 6: 45. doi: 10.1186 1476 - 4598 - 6 - 45. PMC 1964763. PMID 17623056. Human CRABP 1 genome location