ⓘ RAPGEF5

                                     

ⓘ RAPGEF5

Rap guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the RAPGEF5 gene.

The members of the RAS subfamily to see the CRAS, MIM 190020 from GTPase function in signal transduction as GTR / GDP-regulated switches that cycle between inactive GDP and active GTP-bound state. Guanine nucleotide exchange factors GEF, such as RAPGEF5, serve RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between the surface receptors of cells and activation of RAS Rebhun et al. 2000.

                                     
  • exchange factor 2 is a protein that in humans is encoded by the RAPGEF 2 gene. RAPGEF 2 is a cyclic AMP binding protein. Members of the RAS subfamily of
  • that also include C3G RAPGEF1 PDZ - GEF1 RAPGEF2 PDZ - GEF2 RAPGEF 6 Repac RAPGEF5 CalDAG - GEF1 ARHGEF1 CalDAG - GEF3 ARHGEF3 PLCε1 PLCE1 and
  • proteins. KNDC1 PLCE1 RALGDS RALGPS1 RALGPS2 RAPGEF 1 RAPGEF 2 RAPGEF 3 RAPGEF 4 RAPGEF5 RAPGEF 6 RAPGEFL1 RASGEF1A RASGEF1B RASGEF1C RASGRF1
  • GEF 4 RAPGEF 4 also known as exchange protein directly activated by cAMP 2 EPAC2 is a protein that in humans is encoded by the RAPGEF 4 gene. Epac2
  • nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF 6 gene. GRCh38: Ensembl release 89: ENSG00000158987 - Ensembl, May 2017 GRCm38:
  • between performance on the Mooney Face Test and a polymorphism in the RAPGEF5 gene. The Mooney test has been updated by the Mooney - Verhallen test, which
  • nucleotide exchange factor 1 is a protein that in humans is encoded by the RAPGEF 1 gene. The protein encoded by this gene is a human guanine nucleotide releasing
  • KCNH3 KCNH4 KCNH 5 KCNH6 KCNH7 KCNH8 PNPLA6 PNPLA7 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKG1 PRKG2 RAPGEF 2 RAPGEF 3 RAPGEF 4 RAPGEF 6 RCNC2 SLC9A10
  • channels and a few other cyclic nucleotide - binding proteins such as Epac1 and RAPGEF 2. cAMP and its associated kinases function in several biochemical processes