ⓘ SOSTDC1

                                     

ⓘ SOSTDC1

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein BMP antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

                                     
  • subunit RCP9 REPIN 1 replication initiator 1 RNF216 - IT 1 encoding protein RNF216 intronic transcript 1 SCIN: scinderin SCRN 1 secernin 1 SOSTDC1 sclerostin