ⓘ ADH6

                                     

ⓘ ADH6

Alcohol dehydrogenase 6 is an enzyme that in humans is encoded by the ADH6 gene.

This gene encodes class V alcohol dehydrogenase, which is a member of a family of dehydrogenases of alcohol. The members of this family metaboliziruet various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids and lipid peroxidation products. This gene is expressed in the stomach and in the liver, and it contains a glucocorticoid response element in front of its 5 UTR, which is a steroid hormone binding site of the receptor. Deduced amino acid sequence of the open reading frame of this gene shows about 60% positional identity with other known alcohol dehydrogenase. This gene may have separate physiological functions.

                                     
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