ⓘ PCDHB5

                                     

ⓘ PCDHB5

Protocadherin beta-5 is a protein that in humans is encoded by the PCDHB5 gene.

This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that differs from others in the cadherin superfamily. The extracellular Domains interact in a homophilic manner to specify differential cell-cell connections. Unlike alpha and gamma clusters, the transcripts of these genes consist of only one large exon, not sharing common 3 exons as expected. These neural cadherin-cell adhesion proteins are integral proteins of the plasma membrane. Their specific functions are unknown but they are likely to play an important role in the establishment and operation of specific extracellular neural connections.

                                     
  • PCDHA 5 PCDHA6 PCDHA7 PCDHA8 PCDHA9 PCDHA10 PCDHA11 PCDHA12 PCDHA13 PCDHAC1 PCDHAC2 PCDHB 1 PCDHB 2 PCDHB 3 PCDHB 4 PCDHB5 PCDHB 6 PCDHB 7 PCDHB 8 PCDHB 9 PCDHB 10
  • PCDHA 5 PCDHA6 PCDHA7 PCDHA8 PCDHA9 PCDHA10 PCDHA11 PCDHA12 PCDHA13 PCDHAC1 PCDHAC2 PCDHB 1 PCDHB 2 PCDHB 3 PCDHB 4 PCDHB5 PCDHB 6 PCDHB 7 PCDHB 8 PCDHB 9 PCDHB 10
  • Protocadherin beta - 9 is a protein that in humans is encoded by the PCDHB 9 gene. This gene is a member of the protocadherin beta gene cluster, one of three
  • Protocadherin beta - 7 is a protein that in humans is encoded by the PCDHB 7 gene. This gene is a member of the protocadherin beta gene cluster, one of three
  • Protocadherin beta - 12 is a protein that in humans is encoded by the PCDHB 12 gene. This gene is a member of the protocadherin beta gene cluster, one of
  • Protocadherin beta - 11 is a protein that in humans is encoded by the PCDHB 11 gene. This gene is a member of the protocadherin beta gene cluster, one of
  • the PCDHB 14 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome 5 The
  • Protocadherin beta - 3 is a protein that in humans is encoded by the PCDHB 3 gene. This gene is a member of the protocadherin beta gene cluster, one of three
  • Protocadherin beta - 2 is a protein that in humans is encoded by the PCDHB 2 gene. This gene is a member of the protocadherin beta gene cluster, one of three