ⓘ MGAT4B

                                     

ⓘ MGAT4B

Alpha-1.3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B is an enzyme that in humans is encoded by the MGAT4B gene.

This gene encodes a key glycosyltransferase that regulates the formation of three - and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme a, catalyzes the transfer of N-acetylglucosamine from UDP-GlcNAc-GlcNAc in beta 1.4 relationship with a man-alpha-1.3-male-beta-1.4-GlcNAc arm of R-man-alpha-1.6 GlcNAc-beta-1.2-man-alpha-1.3 human beta-1.4-GlcNAc-beta-1.4-GlcNAc-beta-1-ASN. Thus, a protein necessary for the production of tri - and Tetra-antennary sugar chains. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. His affinity for donors of acceptors is slightly lower than MGAT4A therefore, he suggested that it is not the main contribution to N-glycan biosynthesis.

                                     
  • particularly a glycosyltransferase that, in addition to the related isoenzyme B MGAT4B takes part in the transfer of N - acetylglucosamine GlcNAc to the core
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  • 2 - beta - N - acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT 2 gene. The product of this gene is a Golgi enzyme catalyzing an essential
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  • vessicles CLTB Clathrin B vessicles CLTC MTX2 AP2S1 CD81 GPAA1 LGALS9 MGAT 2 MGAT4B VAMP3 CTNNA1 NM 001903 CTNNB1 CTNNBIP1 NM 020248 CTNNBL1 NM 030877 CTNND1
  • obinutuzumab is produced were engineered to overexpress two glycosylation enzymes, MGAT 3 and Golgi mannosidase 2, which reduce the amount of fucose attached to the
  • Uncharacterized Protein KIAA1211 - Like LANCL1: LanC like 1 MALL: MAL - like protein MGAT 5: mannosyl alpha - 1, 6 - - glycoprotein beta - 1, 6 - N - acetyl - glucosaminyltransferase
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