ⓘ GUCY1A3

                                     

ⓘ GUCY1A3

Soluble guanylate cyclase sGC, a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs. Mutations in this gene have been associated to cases of myocardial infarction 10.1038/nature12722.