ⓘ B4GALNT1

                                     

ⓘ B4GALNT1

Beta-1.4 N-acetylgalactosaminyltransferase 1 is an enzyme that in humans is encoded by the B4GALNT1 gene.

GM2 and gd2 gangliosides are sialic acid containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of GM2 and gd2 and glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc in Gm3 and GD3 beta 1.4 relationship, resulting in the synthesis of GM2 and gd2, respectively.