ⓘ PDE10A

                                     

ⓘ PDE10A

cAMP and cAMP-inhibited cGMP 3.5-cyclic phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene.

Various cellular responses are regulated by the second messengers camp and cGMP. Phosphodiesterases, such as PDE10A, eliminate camp - and cGMP-mediated intracellular signaling by hydrolysis of cyclic nucleotides to the corresponding nucleoside 5-Prime monophosphate.