ⓘ XPNPEP1

                                     

ⓘ XPNPEP1

X-prolyl aminopeptidase EC 3.4.11.9 is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine Blau et al., 1988.

                                     
  • by the XPNPEP 3 gene. XPNPEP 3 localizes to mitochondria in renal cells and to kidney tubules in a cell type - specific pattern. Mutations in XPNPEP 3 gene
  • Xaa - Pro aminopeptidase 2 is an enzyme that in humans is encoded by the XPNPEP 2 gene. Aminopeptidase P is a hydrolase specific for N - terminal imido bonds
  • possible for ciliopathies to be associated with unexpected proteins such as XPNPEP 3, which localizes to mitochondria but is believed to affect ciliary function
  • MPPD 1 Protein MPPD 1 Antibody CYB5R3 Gene - GeneCards NB5R3 Protein NB5R3 Antibody FBLN 1 Gene - GeneCards FBLN 1 Protein FBLN 1 Antibody