ⓘ GFRA3

                                     

ⓘ GFRA3

The protein encoded by this gene is a glycosylphosphatidylinositolGPI-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.

                                     
  • neurturin receptor, is a protein that in humans is encoded by the GFRA 2 gene. The GFRA 2 protein is a glycosylphosphatidylinositol GPI - linked cell surface
  • known as the GDNF receptor, is a protein that in humans is encoded by the GFRA 1 gene. Glial cell line - derived neurotrophic factor GDNF and neurturin NTN
  • as the persephin receptor, is a protein that in humans is encoded by the GFRA 4 gene. GFRα GRCh38: Ensembl release 89: ENSG00000125861 - Ensembl, May 2017
  • from 33 stillborn fetuses were sequenced for mutations in RET, GDNF and GFRA 1. Nineteen of the fetuses had BRA, ten had URA and 4 had congenital renal
  • factor GFRa1 GFRa1 GDNF neurturin artemin GFRa 2 GFRa 2 Neurturin GDNF GFRa3 GFRa3 Artemin GFRa 4 GFRa 4 Persephin NPR natriuretic peptide receptor