ⓘ Epithelioid sarcoma

                                     

ⓘ Epithelioid sarcoma

Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by epithelioid-like features. It accounts for less than 1% of all soft tissue sarcomas. It was first clearly characterized by F.M. Enzinger in 1970. It commonly presents itself in the distal limbs of young adults as a small, soft mass or a series of bumps. A proximal version has also been described, frequently occurring in the upper extremities. Rare cases have been reported in the pelvis, vulva, penis, and spine.

Histologically, epithelioid sarcoma forms nodules with Central necrosis surrounded by a soft, polygonal cells with eosinophilic cytoplasm and peripheral spindles. Epithelioid sarcomas typically Express vimentin, cytokeratins, epithelial membrane antigen, and CD34, whereas they are usually negative for S100, desmin, and FLI1 FLI-1. They usually stain positive for CA125.

Epithelioid sarcoma most often affects young people, but no age group is immune. The disease has a tendency to develop local recurrences and metastasis thereafter in regional lymph nodes, lungs, bones, brain, and other places, including the scalp. Generally speaking, epithelioid sarcoma has a high level of recurrences after the primary treatment and usually recurs locally or tumor. Epithelioid sarcoma also demonstrated lymphatic spread in 22-48% of cases and metastases in 21-63% of cases. These activities, as well as the preliminary stage of the progression and aggressiveness of the class, to predict the overall worse result. The overall five-year survival rate for epithelioid sarcoma is anywhere from 25 to 78%. Importantly, 10-year and 15-year survival rate drops significantly. Is associated with a more positive outcome are younger age, female and male, distal and proximal location, the smaller size of the tumor, and negative margins after resection of the tumor.

                                     
  • Epithelioid may refer to: Epithelioid cell, a cell that resembles epithelial cells Epithelioid sarcoma a soft tissue tumour Epithelioid hemangioendothelioma
  • Undifferentiated round cell sarcoma Undifferentiated epithelioid sarcoma Undifferentiated sarcoma not otherwise specified. Symptoms of bone sarcomas typically include
  • treatment regimens. Billings SD, Folpe AL, Weiss SW January 2003 Epithelioid sarcoma - like hemangioendothelioma Am. J. Surg. Pathol. 27 1 48 57. doi: 10
  • started in, but has not yet spread to distant parts of the body epithelioid sarcoma not eligible for complete resection surgically removing all of a
  • Perivascular epithelioid cell tumour, also known as PEComa or PEC tumour, is a family of mesenchymal tumours consisting of perivascular epithelioid cells PECs
  • mixture of spindle, epithelioid and tumor giant cells. Approximately two thirds of the tumors contain melanin pigment. Clear cell sarcoma similar to melanoma
  • Endometrial stromal sarcoma is a malignant subtype of endometrial stromal tumor arising from the stroma connective tissue of the endometrium rather
  • Epithelioid hemangioendothelioma eHAE is a rare tumor, first characterized by Sharon Weiss and Franz Enzinger that both clinically and histologically
  • being informed that epithelioid sarcoma was an extremely rare cancer and difficult to treat. The incidence of epithelioid sarcoma was reported as 0.4
  • rhabdomyosarcoma sarcoma botryoides Leiomyosarcoma Fibrous histiocytoma Proximal epithelioid sarcoma Alveolar soft part sarcoma Liposarcoma Dermatofibrosarcoma
  • is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma - like hemangioendothelioma, other vascular tumors